Corvus (CRVS) is approaching a key inflection point with the upcoming readout from its Phase 1b/2 study of CPI-818 (soquelitinib), an investigational ITK inhibitor, in moderate-to-severe atopic dermatitis. This is the first clinical test of ITK inhibition in a large, chronic inflammatory condition, and investors are watching closely to see whether CPI-818 can offer a differentiated efficacy and safety profile compared to JAK inhibitors. A positive signal, especially in itch relief and skin clearance, could reposition Corvus as a serious player in immunology. Implied volatility is elevated at ~+/-110% into the readout.
Every Monday we are out with public biotech research, profiling biotech companies with near term catalysts. This will focus primarily on the major market moving biotech events such as data readouts from the major scientific conferences as well as potential regulatory approvals.
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HOW TO PLAY BIOTECH APPROVAL/DATA READOUTS ANNOUNCEMENTS
While biotech equities will move on news of announcement, often if there is high conviction in a positive read, a large run up ahead of the news will occur and the actual event turns into a sell the news event. Sometimes, investors wait for the actual event to make a long/short decision. And obviously if the news is disappointing (more often than not) the stock will tank.
This is not financial advice so you will have to make your own call on how to best play these events. Our aim is simply to flag catalysts with high projected volatility.
🚨 ALERT: Ph 1b/2 readout for CPI-818 (soquelitinib; ITKi) in Atopic Dermatitis
📅 DATE: May 8th, 4:30pm PT
📈 IMPLIED VOLATILITY: +/- 110%
BACKGROUND:
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