Preview of the ESMO 2024 Conference

Anticipated Highlights and Key Themes

Hello Avatar!  With ESMO upon us it is sure to be a fun and active weekend for those with laser Oncology focus. The European Society for Medical Oncology (ESMO) conference is one of the main events for sharing clinical, and the depth of content can be overwhelming. We wanted to take a crack at distilling down to the key themes and specific readouts to keep on the radar. We look forward to the discussion on X over the coming days! Please drop a comment if we missed programs you feel are exciting and should be highlighted that we may have missed.

We are now publishing 4-5x per week according to the following cadence:

• Mondays: BioBucks: Stock Analysis & Biotech Catalysts

• Wednesdays: CRISPR Corner: Monthly gene editing news

• Thursdays: Insiders Track: Public & Private Biotech Markets

• Fridays: Sweat Equity: Your Weekly Biotech Fix

• Sundays: Building Biotech: Strategic Topics

This Sunday’s Building Biotech strategy discussion will be an educational one for the students where we will share our PhD Survival guide.

Monday’s BioBucks column will feature Zevra Therapeutics has an upcoming PDUFA decision for arimoclomol as a treatment for Niemann-Pick Disease Type C. With options pricing indicating an astounding 65% volatility, the market is bracing for significant movement. 

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The European Society for Medical Oncology (ESMO) conference, set to take place in Barcelona, Spain, from September 13-17, 2024, has solidified its reputation as a cornerstone event in the oncology community. Rivaling the annual meeting of the American Society of Clinical Oncology (ASCO), ESMO serves as a global platform where groundbreaking research, clinical trial results, and innovative therapies are unveiled. This conference is crucial for oncologists, researchers, pharmaceutical companies, and other stakeholders dedicated to advancing cancer treatment and improving patient outcomes worldwide.

This year's conference is poised to deliver a wealth of information across various oncology domains. Notably, several studies have been selected for the prestigious presidential or plenary sessions, indicating their potential to significantly influence clinical practice. Below is a detailed overview of the most anticipated themes and data presentations that will be featured at ESMO 2024.

Key themes include:

1. Immuno-Oncology

   1. TIGIT

   2. LAG3

2. Antibody Drug Conjugates (ADCs)

   1. EGFRxHER3

   2. FTa

   3. B7-H3/4

3. Target Protein Degradation (TPD)

   1. KRAS G12D

   2. BRAFV600

   3. AR

   4. SMARCA2

4. Novel Approaches

   1. PD(L)-1 xVEGF

   2. MAGE TCR

   3. Cytokines IL7

Immuno-Oncology Breakthroughs